Build a Model Based on In Vitro Data
Summary: In this tutorial, you will build a predictive model based on in-vitro data using OpenTox web services by means of both a Graphical User Interface (GUI) and the command line. Several models can be built and inspected.
Objective:
Learn to handle searching facilities, data representation, and API of the OpenTox framework, specifically in the context of in-vitro data.
Steps:
1. Inspect data from US EPA's Toxcast Program.
2. Select in vitro assays based on correlation to an in-vivo endpoint.
3. Use the ToxCreate webapplication to create a model
a. Fill the data into an Excel Sheet
b. Create the model
c. Make a prediction
4. Create a model using the Opentox API
a. Locate data on the ambit webservice.
b. Create a model on the command line using curl.
c. Make a prediction.
