OpenTox Blog
This blog is a collective open blog for the community to post news, scientific developments and results, comments, opinions, insights, links and discussions related to computer-based predictive toxicology. (For new users: you will also be able to post here once the webmaster has added you to the user group.)
To create a new blog entry follow the following link:
Collaborative development of predictive toxicology applications
The following initial paper on OpenTox has now been published and is available in preliminary form:
Collaborative development of predictive toxicology applications
Barry Hardy, Nicki Douglas, Christoph Helma, Micha Rautenberg, Nina Jeliazkova, Vedrin Jeliazkov, Ivelina Nikolova, Romualdo Benigni, Olga Tcheremenskaia, Stefan Kramer, Tobias Girschick, Fabian Buchwald, Joerg Wicker, Andreas Karwath, Martin Gutlein, Andreas Maunz, Haralambos Sarimveis, Georgia Melagraki, Antreas Afantitis, Pantelis Sopasakis, David Gallagher, Vladimir Poroikov, Dmitry Filimonov, Alexey Zakharov, Alexey Lagunin, Tatyana Gloriozova, Sergey Novikov, Natalia Skvortsova, Dmitry Druzhilovsky, Sunil Chawla, Indira Ghosh, Surajit Ray, Hitesh Patel and Sylvia Escher
Journal of Cheminformatics 2010, 2:7 (31 August 2010)
http://www.jcheminf.com/content/2/1/7
Please feel free to circulate in the community and to your contacts who might be interested. Thanks!
A special thanks to all you have contributed to advancing this work, including our advisors, and growing community of friends, interactions and partners!
Barry
Integrating Predictive Toxicology Resources and Applications
This workshop will provide a forum for discussion of the integrating resource and application needs of today's predictive toxicology researchers. We will discuss issues and solutions for the more effective support, management and exploitation of predictive toxicology resources created by international research projects and solution developers. Discussions will include requirements and collaboration opportunities in the areas of interoperable resources for data, models and applications supported by public standards, interfaces, vocabularies and ontologies, and best practice approaches in computer science and engineering. Stakeholder perspectives from industry, regulatory, and academic research viewpoints will be shared. Participants will engage in Knowledge Café discussions to discuss user requirements in interdisciplinary science and integrated testing strategies and to determine promising future strategies, directions and actions.
Those features on the box
Something for both sides of the OpenTox boxes to be thinking ahead about :)!
Development and Use of Predictive Toxicology Applications
On the 19th September we will hold a one day OpenTox pre-conference workshop on the Development and Use of Predictive Toxicology Applications, which will take place ahead of the 18th European Symposium on QSAR, 19-24 September, Rhodes, Greece.
OpenTox Collaboration Pool
We are establishing an OpenTox Collaboration Pool of individuals and organisations who have an interest in collaborating together in the area of predictive toxicology.
Integrated Predictive Toxicology Application Development
Presentation by Barry Hardy on the philosophy, design and methods being used in creating the OpenTox Framework as a "Linux for Predictive Toxicology".
OpenTox Use Cases and Knowledge Café Groups
I summarise here the Use Cases we will discuss at the OpenTox workshop on predictive toxicology in Rome, and including information on format and discussion groups.
Molecular Editors
I have collected a few links concerning molecular editors/viewers that could be relevant for OpenTox.
Satisfying REACH Requirements in Predictive Toxicology
The OpenTox Workshop "Satisfying REACH Requirements in Predictive Toxicology" will take place 10-11 September 2009 at the Istituto Superiore di Sanità, Rome, Italy. Participants at the workshop will involve cross-industry users and regulatory experts in addition to solution developers and providers who will discuss the requirements and use cases of users in chemical toxicology evaluation and risk assessment, and including satisfaction of current and future requirements of the REACH legislation using alternative testing methods. The workshop format involves short presentations to provide user, regulatory and solution needs perspectives, followed by knowledge cafe discussions discussing use cases, challenges, issues, solutions, collaboration opportunities and ways forward in small groups.
New OpenTox website
On 14 August 09 we opened this new OpenTox community website and welcome its future use for members of the international community. The site is intended to provide resources of interest to users, application developers, regulators and researchers in computer-based predictive toxicology. As the site is new there will be ongoing work in coming weeks on organising and adding resources to the site, so please be patient as you may not find everything you are looking for immediately!
One first step you could take as a site user is to complete your profile - click on the link to your name at the top of the page, and you will be able to edit your profile and preferences.
The Development section of the site is now open, and ongoing technical contributions and discussions can be made there in the wiki, mailing lists and documents area.
Please feel free to contact me with any questions you have!
Barry Hardy
OpenTox Coordinator
Barry.Hardy -(at)- douglasconnect.com
