You are here: Home » OpenTox Blog

OpenTox Blog

— filed under:

This blog is a collective open blog for the community to post news, scientific developments and results, comments, opinions, insights, links and discussions related to computer-based predictive toxicology. (For new users: you will also be able to post here once the webmaster has added you to the user group.)

To create a new blog entry follow the following link: 

New Blog Entry

Collaborative development of predictive toxicology applications

Posted by Barry Hardy at Aug 31, 2010 08:26 PM |

The following initial paper on OpenTox has now been published and is available in preliminary form:

Collaborative development of predictive toxicology applications
Barry Hardy, Nicki Douglas, Christoph Helma, Micha Rautenberg, Nina Jeliazkova, Vedrin Jeliazkov, Ivelina Nikolova, Romualdo Benigni, Olga Tcheremenskaia, Stefan Kramer, Tobias Girschick, Fabian Buchwald, Joerg Wicker, Andreas Karwath, Martin Gutlein, Andreas Maunz, Haralambos Sarimveis, Georgia Melagraki, Antreas Afantitis, Pantelis Sopasakis, David Gallagher, Vladimir Poroikov, Dmitry Filimonov, Alexey Zakharov, Alexey Lagunin, Tatyana Gloriozova, Sergey Novikov, Natalia Skvortsova, Dmitry Druzhilovsky, Sunil Chawla, Indira Ghosh, Surajit Ray, Hitesh Patel and Sylvia Escher
Journal of Cheminformatics 2010, 2:7 (31 August 2010)

Please feel free to circulate in the community and to your contacts who might be interested. Thanks!

A special thanks to all you have contributed to advancing this work, including our advisors, and growing community of friends, interactions and partners!


Integrating Predictive Toxicology Resources and Applications

Posted by Barry Hardy at Apr 25, 2010 12:55 PM |

This workshop will provide a forum for discussion of the integrating resource and application needs of today's predictive toxicology researchers. We will discuss issues and solutions for the more effective support, management and exploitation of predictive toxicology resources created by international research projects and solution developers. Discussions will include requirements and collaboration opportunities in the areas of interoperable resources for data, models and applications supported by public standards, interfaces, vocabularies and ontologies, and best practice approaches in computer science and engineering. Stakeholder perspectives from industry, regulatory, and academic research viewpoints will be shared. Participants will engage in Knowledge Café discussions to discuss user requirements in interdisciplinary science and integrated testing strategies and to determine promising future strategies, directions and actions.

Read More…

Those features on the box

Posted by Barry Hardy at Mar 15, 2010 04:55 PM |

Something for both sides of the OpenTox boxes to be thinking ahead about :)!

Read More…

Development and Use of Predictive Toxicology Applications

Posted by Barry Hardy at Mar 03, 2010 07:50 PM |

On the 19th September we will hold a one day OpenTox pre-conference workshop on the Development and Use of Predictive Toxicology Applications, which will take place ahead of the 18th European Symposium on QSAR, 19-24 September, Rhodes, Greece.

Read More…

OpenTox Collaboration Pool

Posted by Barry Hardy at Feb 13, 2010 10:07 AM |

We are establishing an OpenTox Collaboration Pool of individuals and organisations who have an interest in collaborating together in the area of predictive toxicology.

Read More…

Integrated Predictive Toxicology Application Development

Posted by Barry Hardy at Dec 08, 2009 12:38 PM |

Presentation by Barry Hardy on the philosophy, design and methods being used in creating the OpenTox Framework as a "Linux for Predictive Toxicology".

Read More…

OpenTox API (Second Version)

Posted by Barry Hardy at Dec 01, 2009 06:14 AM |

The second version of the OpenTox API is available.

Read More…

OpenTox Use Cases and Knowledge Café Groups

Posted by Barry Hardy at Sep 05, 2009 03:40 PM |

I summarise here the Use Cases we will discuss at the OpenTox workshop on predictive toxicology in Rome, and including information on format and discussion groups.

Read More…

Molecular Editors

Molecular Editors

Posted by Maunz Andreas at Sep 04, 2009 10:05 AM |

I have collected a few links concerning molecular editors/viewers that could be relevant for OpenTox.

Read More…

Satisfying REACH Requirements in Predictive Toxicology

Posted by Barry Hardy at Aug 17, 2009 04:40 PM |

The OpenTox Workshop "Satisfying REACH Requirements in Predictive Toxicology" will take place 10-11 September 2009 at the Istituto Superiore di Sanità, Rome, Italy. Participants at the workshop will involve cross-industry users and regulatory experts in addition to solution developers and providers who will discuss the requirements and use cases of users in chemical toxicology evaluation and risk assessment, and including satisfaction of current and future requirements of the REACH legislation using alternative testing methods. The workshop format involves short presentations to provide user, regulatory and solution needs perspectives, followed by knowledge cafe discussions discussing use cases, challenges, issues, solutions, collaboration opportunities and ways forward in small groups.

Read More…

New OpenTox website

Posted by Barry Hardy at Aug 15, 2009 12:11 PM |

On 14 August 09 we opened this new OpenTox community website and welcome its future use for members of the international community.  The site is intended to provide resources of interest to users, application developers, regulators and researchers in computer-based predictive toxicology.  As the site is new there will be ongoing work in coming weeks on organising and adding resources to the site, so please be patient as you may not find everything you are looking for immediately!

One first step you could take as a site user is to complete your profile - click on the link to your name at the top of the page, and you will  be able to edit your profile and preferences. 

The Development section of the site is now open, and ongoing technical contributions and discussions can be made there in the wiki, mailing lists and documents area.

Please feel free to contact me with any questions you have!

Barry Hardy

OpenTox Coordinator

Barry.Hardy -(at)-

Document Actions