Activity

Evaluation of the Final Implementation

OpenTox D1.4 Report on Evaluation of the Final Implementation

Collaborative Virtual Organisation and Infrastructure for Anti-Malarial Drug Design

Presentation by Barry Hardy at the BIO-IT Europe 2011 conference in Hannover, 12 October 2011, in the Collaborative Drug Design program. OpenTox is contributing to the Scientists Against Malaria initiative through the holistic incorporation of predictive toxicology modelling of drug design libraries using weight of evidence–based workflows across public and commercial resources.

Presentations

folder for presentation materials

Effects Respiratory Tract (owl)

 

Organ Endpoints Ontology (owl)

 

Toxicological Endpoints Ontology (owl)

 

Bio Ontology 2011 Slides

 

OpenTox Bio Ontologies 2011 Article

 

RDF Representation

Description of all OpenTox resources and their relationships in an OWL ontology. Examples for object representations in RDF/XML

Task

Asynchronous jobs are handled via an intermediate Task resource. A resource, submitting an asynchronous job should return the URI of the task.

Interfaces Discussion

Section for posting experiences, proposals and discussion related to OpenTox interfaces

Validation

 

Model

Provides access to OpenTox prediction models

Algorithm ontology

 

Algorithm

Provides access to OpenTox algorithms

Dataset

Provides access to chemical compounds and their features (e.g. structural, physical-chemical, biological, toxicological properties)

Chemical features

 

Biological and Toxicological Features

 

Feature ontology

Related work and existing ontologies

Feature