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OpenTox Ontology Description

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The goal of OpenTox  is to develop an interoperable predictive toxicology framework with multiple web services providing users access to distributed toxicological resources including data, computer models, validation and reporting. OpenTox applications are based on use cases that satisfy user needs in predictive toxicology. The definition of ontology and controlled vocabulary is extremely important to the construction of the OpenTox data infrastructure. It contributes to the necessary standardization and rational organization of data, describing and linking toxicological endpoints information in a formal way, suitable for being processed automatically by the software, with minimal human interaction.
Besides a ontology for toxicological endpoints and  Organs and Effects Ontology, a formal OWL representation of modeling algorithms is available on the OpenTox website


The collaborative work on the project is curated using the Collaborative Protégé Editor Collaborative Protege, with different access privileges . The ontology is open for community reviews and annotations.


The toxicological endpoints ontology and  Organs and Effects Ontology ontology are also available in OWL from OWL files repository.

Protégé, a free, open source visual ontology editor could be used to open, browse and edit these OWL files.





OpenTox Predictive Toxicology Framework: toxicological ontology and semantic media wiki-based OpenToxipedia, Bio-ontologies 2011. 15-16 July, Vienna, Austria


Bio-ontology 2011_slides.pdf 


Collaborative Ontology Design and Implementation for the OpenTox Predictive Toxicology Framework, Bio-ontologies 2010, 9-10 July, Boston MA

Poster: Collaborative Ontology Design and Implementation for the Open- Tox Predictive Toxicology Framework

Abstract: Collaborative Ontology Design and Implementation for the Open- Tox Predictive Toxicology Framework


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