10. Complement your findings with predicted associations with hepatobiliary adverse events
We have used Pharmatrope's Titanium Models to predict the association of the TCAMS compounds with 19 selected hepatobiliary adverse events:
- Hepatic function abnormal
- Liver disorder
- Cytolytic hepatitis
- Hepatitis
- Hepatitis acute
- Hepatitis toxic
- Cholestasis
- Jaundice
- Hepatitis cholestatic
- Jaundice cholestatic
- Yellow skin
- Hepatic failure
- Hepatitis fulminant
- Acute hepatic failure
- Hepatorenal failure
- Hepatotoxicity
- Hepatomegaly
- Hyperbilirubinaemia
- Hepatosplenomegaly
Complement the your findings on the TCAMS subset using the file at this link. The document contains a list with each compound of the TCAMS subset we have worked with in this exercise, together with the number of adverse events (out of the 19 listed above) Titanium predicts each compound to be associated with (only associations considered statistically relevant are counted).
Please fill out the Evaluation Form.
