Use lazar-GUI for predictions with QSAR models based on the lazar-OpenTox framework.
Micha Rautenberg and David Vorgrimmler (in silico toxicology)
lazar (lazy structure–activity relationships) is a modular framework for predictive toxicology. Similar to the read across procedure in toxicological risk assessment, lazar creates local QSAR (quantitative structure–activity relationship) models for each compound to be predicted. Model developers can choose between a large variety of algorithms for descriptor calculation and selection, chemical similarity indices, and model building.
lazar-GUI is a graphical webinterface for the lazar framework, which enables user to make predictions on existing QSAR models.
In this workshop participants will use the lazar-GUI to make predictions for chemical compounds on classification and regression models. The available models are based on the lazar-OpenTox framework.
