OpenTox 2011 Knowledge Cafe
Participants will discuss a range of topics in predictive toxicology in small groups.
Topics
A. Mechanistic Strategies - What are the key innovations needed to accelerate progress?
B. Predictive Metabolism - What is needed for a complete and reliable prediction of metabolites?
C. Computational Chemistry - Emerging challenges and opportunities in receptor-mediated predictive toxicology
D. Systems Biology - How can we bridge the divide between modelling molecular pathways and quantitative prediction at the organelle level?
E. Regulatory Needs - How do we accelerate the acceptance of emerging scientific methods in regulatory applications?
F. Kinetics - Extrapolating in vitro data to model human hazard and exposure
G. Weight of Evidence - Developing holistic approaches to compound profiling and prioritisation decision making
H. Read Across and Categories - What are the key components for a more rigorous approach to a best practice?
